Oral administration of swine gastric mucin alters levels of serum and urine nitric oxide, and lipid metabolism in mice.

Mice were fed with swine gastric mucin in a basal diet for 5 weeks. In 5 week-old mice, a 2% mucin diet significantly decreased nitric oxide levels of serum and liver. Reduction of serum total cholesterol and triglyceride and increase of HDL-cholesterol level were also significant with the mucin diet. In 14 month-old mice, the mucin diet was less effective.